July 26, 2022
SATB2 preserves colon stem cell identity and mediates ileum-colon conversion via enhancer remodeling
https://pubmed.ncbi.nlm.nih.gov/34582804/
Wei Gu 1, Hua Wang 2, Xiaofeng Huang 1, Judith Kraiczy 3, Pratik N P Singh 3, Charles Ng 4, Sezin Dagdeviren 5, Sean Houghton 1, Oscar Pellon-Cardenas 6, Ying Lan 1, Yaohui Nie 1, Jiaoyue Zhang 1, Kushal K Banerjee 3, Emily J Onufer 7, Brad W Warner 7, Jason Spence 8, Ellen Scherl 4, Shahin Rafii 1, Richard T Lee 5, Michael P Verzi 6, David Redmond 1, Randy Longman 4, Kristian Helin 9, Ramesh A Shivdasani 3, Qiao Zhou 10
Affiliations collapse
Affiliations
- 1Division of Regenerative Medicine & Ansary Stem Cell Institute, Department of Medicine, Weill Cornell Medicine, 1300 York Avenue, New York, NY 10065, USA.
- 2Cell Biology Program and Center for Epigenetics Research, Memorial Sloan Kettering Cancer Center, 430 E 67th Street, New York, NY 10065, USA.
- 3Department of Medical Oncology, Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA.
- 4Jill Roberts Center for Inflammatory Bowel Disease, Weill Cornell Medicine, 1283 York Avenue, New York, NY 10065, USA.
- 5Department of Stem Cell and Regenerative Biology, Harvard University, 7 Divinity Avenue, Cambridge, MA 02138, USA.
- 6Department of Genetics, Rutgers University, 145 Bevier Road, Piscataway, NJ 08854, USA.
- 7Division of Pediatric Surgery, Department of Surgery, Washington University School of Medicine, 660 S. Euclid Avenue, St. Louis, MO 63110, USA.
- 8Department of Internal Medicine, University of Michigan, 1500 E. Medical Center Drive, Ann Arbor, MI 48109, USA.
- 9Cell Biology Program and Center for Epigenetics Research, Memorial Sloan Kettering Cancer Center, 430 E 67th Street, New York, NY 10065, USA; Biotech Research and Innovation Centre (BRIC), University of Copenhagen, Copenhagen N 2200, Denmark; The Novo Nordisk Foundation for Stem Cell Biology (Danstem), University of Copenhagen, Copenhagen N 2200, Denmark.
- 10Division of Regenerative Medicine & Ansary Stem Cell Institute, Department of Medicine, Weill Cornell Medicine, 1300 York Avenue, New York, NY 10065, USA. Electronic address: jqz4001@med.cornell.edu.
Rapid establishment of human colonic organoid knockout lines
https://pubmed.ncbi.nlm.nih.gov/35463469/
Affiliations collapse
Affiliations
- 1Division of Regenerative Medicine & Ansary Stem Cell Institute, Department of Medicine, Weill Cornell Medicine, 1300 York Avenue, New York, NY 10065, USA.
- 2Department of Internal Medicine, University of Michigan, 1500 E Medical Center Drive, Ann Arbor, MI 48109, USA.