Publications

Gu W, Huang X, Singh PNP, Li S, Lan Y, Deng M, Lacko LA, Gómez-Salinero JM, Rafii S, Verzi MP et al..  2024.  A MTA2-SATB2 chromatin complex restrains colonic plasticity toward small intestine by retaining HNF4A at colonic chromatin.. Nat Commun. 15(1):3595.

Huang X, Gu W, Zhang J, Lan Y, Colarusso JL, Li S, Pertl C, Lu J, Kim H, Zhu J et al..  2023.  Stomach-derived human insulin-secreting organoids restore glucose homeostasis.. Nat Cell Biol.

Colarusso JL, Zhou Q.  2022.  Direct Reprogramming of Different Cell Lineages into Pancreatic β-Like Cells.. Cell Reprogram. 24(5):252-258.

Gu W, Colarusso JL, Dame MK, Spence JR, Zhou Q.  2022.  Rapid establishment of human colonic organoid knockout lines.. STAR Protoc. 3(2):101308.

Nasteska D, Fine NHF, Ashford FB, Cuozzo F, Viloria K, Smith G, Dahir A, Dawson PWJ, Lai Y-C, Bastidas-Ponce A et al..  2021.  PDX1 LOW MAFA LOW β-cells contribute to islet function and insulin release. Nature Communications.

Zhao H, Huang X, Liu Z, Pu W, Lv Z, He L, Li Y, Zhou Q, Lui KO, Zhou B.  2021.  Pre-existing beta cells but not progenitors contribute to new beta cells in the adult pancreas.. Nat Metab.

Gu W, Wang H, Huang X, Kraiczy J, Singh PNP, Ng C, Dagdeviren S, Houghton S, Pellon-Cardenas O, Lan Y et al..  2021.  SATB2 preserves colon stem cell identity and mediates ileum-colon conversion via enhancer remodeling.. Cell Stem Cell.

Palikuqi B, Nguyen D-HT, Li G, Schreiner R, Pellegata AF, Liu Y, Redmond D, Geng F, Lin Y, Gómez-Salinero JM et al..  2020.  Adaptable haemodynamic endothelial cells for organogenesis and tumorigenesis.. Nature. 585(7825):426-432.

Zhou Q, Melton.  2018.  Pancreas regeneration.. Nature. 557(7705):351-358.

Tripathi P, Rodriguez-Muela N, Klim JR, A de Boer S, Agrawal S, Sandoe J, Lopes CS, Ogliari KSassi, Williams LA, Shear M et al..  2017.  Reactive Astrocytes Promote ALS-like Degeneration and Intracellular Protein Aggregation in Human Motor Neurons by Disrupting Autophagy through TGF-β1.. Stem Cell Reports. 9(2):667-680.

Zhou Q.  2017.  Regenerative medicine: Interspecies pancreas transplants.. Nature. 542(7640):168-169.

Cavelti-Weder C, Zumsteg A, Li W, Zhou Q.  2017.  Reprogramming of Pancreatic Acinar Cells to Functional Beta Cells by In Vivo Transduction of a Polycistronic Construct Containing Pdx1, Ngn3, MafA in Mice.. Curr Protoc Stem Cell Biol. 40:4A.10.1-4A.10.12.

Cavelti-Weder C, Li W, Zumsteg A, Stemann-Andersen M, Zhang Y, Yamada T, Wang M, Lu J, Jermendy A, Bee YMong et al..  2016.  Hyperglycaemia attenuates in vivo reprogramming of pancreatic exocrine cells to beta cells in mice.. Diabetologia. 59(3):522-32.

Ariyachet C, Tovaglieri A, Xiang G, Lu J, Shah MS, Richmond CA, Verbeke C, Melton DA, Stanger BZ, Mooney D et al..  2016.  Reprogrammed Stomach Tissue as a Renewable Source of Functional β Cells for Blood Glucose Regulation.. Cell Stem Cell. 18(3):410-21.

Yamada T, Cavelti-Weder C, Caballero F, Lysy PA, Guo L, Sharma A, Li W, Zhou Q, Bonner-Weir S, Weir GC.  2015.  Reprogramming Mouse Cells With a Pancreatic Duct Phenotype to Insulin-Producing β-Like Cells.. Endocrinology. 156(6):2029-38.

Li W, Nakanishi M, Zumsteg A, Shear M, Wright C, Melton DA, Zhou Q.  2014.  In vivo reprogramming of pancreatic acinar cells to three islet endocrine subtypes.. Elife. 3:e01846.

Li W, Cavelti-Weder C, Zhang Y, Zhang Y, Clement K, Donovan S, Gonzalez G, Zhu J, Stemann M, Xu K et al..  2014.  Long-term persistence and development of induced pancreatic beta cells generated by lineage conversion of acinar cells.. Nat Biotechnol. 32(12):1223-30.

Zhou Q, Tripathi P.  2012.  How to remake a fibroblast into a neural stem cell.. Cell Stem Cell. 10(4):347-8.