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Reference: SATB2 preserves colon stem cell identity and mediates ileum-colon conversion via enhancer remodelingWei Gu, Hua Wang, Xiaofeng Huang, Judith Kraiczy, Pratik NP Singh, Charles Ng, Sezin Dagdeviren, Sean Houghton, Oscar Pellon-Cardenas, Ying Lan, Yaohui Nie, Jiaoyue Zhang, Kushal K Banerjee, Emily J Onufer, Brad W Warner, Jason Spence, Ellen Scherl,...

https://www.nature.com/articles/d41586-020-01801-y

Forkhead BioTherapeutics is a spin-off from Columbia University in New York City.

You can’t live without insulin. When people with type 1 diabetes lose their ability to produce this hormone, they need to inject synthetic insulin multiple times a day and closely monitor their blood sugar levels. Managing the disease is difficult, and people with diabetes are at high...

Until the day it dies, a cell that has become a skin cell remains a skin cell — or so scientists used to think. Over the past decade, it has become clear that cel- lular identity is not written in stone but can be rewritten by activating specific genetic pro- grams. Today, the field of regenerative medi- cine faces a question: should this rewriting take...

Lab TV News – Video Interview – 2016

"Mini-Stomach" can end Insulin Shots