Zhou Lab

News

Wei and Xiaofeng’s study on a new chromatin complex that controls colon mucosal tissue identity is now published is Nature Communications

May 30, 2024

Click here for the full text.

A MTA2-SATB2 chromatin complex restrains colonic plasticity toward small intestine by retaining HNF4A at colonic chromatin. https://doi.org/10.1038/s41467-024-47738-y

2024 New Year Celebration!

January 2, 2024

2024

ASGCT (American Society of Gene & Cell Therapy) 2023 Annual Meeting in Los Angeles

May 22, 2023

ASGCT 2023 Annual Meeting in Los Angeles

Joe hosted Dr. Spence for a seminar

May 18, 2023

jason

We introduced the Human Therapeutic Organoid Core @Weill Cornell

May 5, 2023

coreSugar

Xiaofeng presented the study of GINS organoids at the 4th IPITA/HSCI/JDRF Summit on Stem Cell Derived Beta Cells

April 26, 2023

Abstract of the presentatoin: https://app.betacells.org/virtual/lecture/33 the 4th IPITA/HSCI/JDRF Summit on Stem Cell Derived Beta Cells

We presented our work about GINS organoids at Ask the Expert hosted by the(sugar)science

April 18, 2023

thesugarscience

We presented our works at Keystone Stem Cells and Organoids Joint Meeting

March 7, 2023

Dr. Qiao Joe Zhou presented "The Molecular Machinery Controlling Stem Cell and Tissue Plasticity Between Adult Colon and Small Intestine".

Dr. Xiaofeng Steve Huang presented "Redirecting differentiation of human stomach stem cells to produce pancreatic islet-like organoids for diabetes treatment".

...

Joe hosted Dr. Jensen for a seminar

February 20, 2023

Kim

PDF flyer: ...

Joe hosted Dr. Michael Shen for a seminar

February 17, 2023

Congratulation to Xiaofeng! His paper “Stomach-derived human Insulin-secreting organoids restore glucose homeostasis” has been accepted by Nature Cell Biology. A preprint is posted on BioRxiv

January 24, 2023

GINS generation

Can't wait to read our preprint? Click here!

Need a tweetorial? Click here...

Wei and Xiaofeng’s study on a new chromatin complex that controls colon mucosal tissue identity is posted on BiorRxiv

January 23, 2023

To read our prerint, please click here!

Let's celebrate the Year of the Rabbit!

January 20, 2023

2023team

Joe Zhou and Remi Creusot organized the 2nd Symposium of the NYC*T1D Network (Type 1 Diabetes in New York City) at the New York Stem Cell Foundation. We have over 20 laboratories and 3 foundations participating.

September 26, 2022

NYC_T1D Network

Congratulations to Xiaofeng! He won the second place of oral presentation in Postdoc Research Day 2022!

September 23, 2022

Xiaofeng Postdoc Research Day 2022

Dr. Xiaofeng Steve Huang presented his work “Restoring Glucose Homeostasis with Stomach-derived Human Insulin-Secreting Organoids” in 2022 Annual Investigator Hybrid Meeting of Human Islet Research Network (HIRN).

September 23, 2022

hirn2022

Dr. Xiaofeng Huang presented his work "Redirecting differentiation of human stomach stem cells to produce pancreatic islet-like organoids for diabetes treatment" in Gordon Research Conference

September 23, 2022

grc2022

Dr. Joe Zhou presented Dr. Wei Gu's work "SATB2 controls colon vs small intestine stem cell identity" in Gordon Research Conference

September 23, 2022

grc2022

July 2022, congratulations to Jonathan Colarusso concluding 2 years as a Research Assistant and starting his medical school.

July 26, 2022

Wei’s CSC paper published in January 2022 and STAR protocol in June 2022

July 26, 2022

SATB2 preserves colon stem cell identity and mediates ileum-colon conversion via enhancer remodeling

https://pubmed.ncbi.nlm.nih.gov/34582804/

Presentation of the Satb2 paper (Wei Gu et al, Cell Stem Cell, 2022) on JRNL

July 25, 2022

Video of Gu W, SATB2 preserves colon stem cell identity and mediates ileum-colon conversion via enhancer remodeling

Speaker: Dr. Wei Gu

March 2022, Welcome Tao and Capucine to the lab as postdoctoral fellows.

March 1, 2022

Researchers Discover the Role the Gene SATB2 Plays in the Colon Lining

October 28, 2021

Reference: SATB2 preserves colon stem cell identity and mediates ileum-colon conversion via enhancer remodeling. Wei Gu, Hua Wang, Xiaofeng Huang, Judith Kraiczy, Pratik NP Singh, Charles Ng, Sezin Dagdeviren, Sean Houghton, Oscar Pellon-Cardenas, Ying Lan, Yaohui Nie, Jiaoyue Zhang, Kushal K Banerjee, Emily J Onufer, Brad W Warner, Jason Spence, Ellen Scherl,...

Comments on Forkhead BioTherapeutics

March 18, 2021

https://www.nature.com/articles/d41586-020-01801-y

Forkhead BioTherapeutics is a spin-off from Columbia University in New York City.

You can’t live without insulin. When people with type 1 diabetes lose their ability to produce this hormone, they need to inject synthetic insulin multiple times a day and closely monitor their blood sugar levels. Managing the disease is difficult, and people with diabetes are at high...

A Simpler Twist of Fate

March 2, 2019

Until the day it dies, a cell that has become a skin cell remains a skin cell — or so scientists used to think. Over the past decade, it has become clear that cel- lular identity is not written in stone but can be rewritten by activating specific genetic pro- grams. Today, the field of regenerative medi- cine faces a question: should this rewriting take...

News

Wei and Xiaofeng’s study on a new chromatin complex that controls colon mucosal tissue identity is now published is Nature Communications

2024 New Year Celebration!

ASGCT (American Society of Gene & Cell Therapy) 2023 Annual Meeting in Los Angeles

Joe hosted Dr. Spence for a seminar

We introduced the Human Therapeutic Organoid Core @Weill Cornell

Xiaofeng presented the study of GINS organoids at the 4th IPITA/HSCI/JDRF Summit on Stem Cell Derived Beta Cells

We presented our work about GINS organoids at Ask the Expert hosted by the(sugar)science

We presented our works at Keystone Stem Cells and Organoids Joint Meeting

Joe hosted Dr. Jensen for a seminar

Joe hosted Dr. Michael Shen for a seminar

Congratulation to Xiaofeng! His paper “Stomach-derived human Insulin-secreting organoids restore glucose homeostasis” has been accepted by Nature Cell Biology. A preprint is posted on BioRxiv

Wei and Xiaofeng’s study on a new chromatin complex that controls colon mucosal tissue identity is posted on BiorRxiv

Let's celebrate the Year of the Rabbit!

Joe Zhou and Remi Creusot organized the 2nd Symposium of the NYC*T1D Network (Type 1 Diabetes in New York City) at the New York Stem Cell Foundation. We have over 20 laboratories and 3 foundations participating.

Congratulations to Xiaofeng! He won the second place of oral presentation in Postdoc Research Day 2022!

Dr. Xiaofeng Steve Huang presented his work “Restoring Glucose Homeostasis with Stomach-derived Human Insulin-Secreting Organoids” in 2022 Annual Investigator Hybrid Meeting of Human Islet Research Network (HIRN).

Dr. Xiaofeng Huang presented his work "Redirecting differentiation of human stomach stem cells to produce pancreatic islet-like organoids for diabetes treatment" in Gordon Research Conference

Dr. Joe Zhou presented Dr. Wei Gu's work "SATB2 controls colon vs small intestine stem cell identity" in Gordon Research Conference

July 2022, congratulations to Jonathan Colarusso concluding 2 years as a Research Assistant and starting his medical school.

Wei’s CSC paper published in January 2022 and STAR protocol in June 2022

SATB2 preserves colon stem cell identity and mediates ileum-colon conversion via enhancer remodeling

Presentation of the Satb2 paper (Wei Gu et al, Cell Stem Cell, 2022) on JRNL

Video of Gu W, SATB2 preserves colon stem cell identity and mediates ileum-colon conversion via enhancer remodeling

March 2022, Welcome Tao and Capucine to the lab as postdoctoral fellows.

Researchers Discover the Role the Gene SATB2 Plays in the Colon Lining

Comments on Forkhead BioTherapeutics

A Simpler Twist of Fate

Insulin from Mini Stomach

BBC The NakedScientist – Radio Interview and Podcast – 2017

NPR Science Friday – Radio Interview – 2017

Lab TV News – Video Interview – 2016

"Mini-Stomach" can end Insulin Shots